Imaging where cancer drugs go in the body could improve treatment - (Science Daily via NewsPoints Desk)

  • Researchers report in the journal ACS Nano a new step toward seeing where certain cancer drugs accumulate in the body in order to better treat patients, Science Daily reported.

  • Specifically, the researchers developed a simple method to attach labels to aminobisphosphonates and extended the method to liposome-entrapped doxorubicin.

  • The labels could then be tracked using positron emission tomography (PET) to see where they go within the body.

  • In mouse models of breast and ovarian cancer, PET imaging showed that the drugs accumulated in tumours and metastatic tissues in varying concentrations and, in most cases, at levels well above those in normal tissues.

  • In one mouse strain, the nanomedicines showed up in the uterus, which would not have been detected without conducting the imaging study, according to the researchers. 

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