Pankiller Abuse Spurs Search for a Safer Opioid Therapy - (Bloomberg via NewsPoints Desk)

  • Backed by a US campaign to lower the abuse of prescription pain drugs, pharmaceutical companies are devising new forms of the medicines that don't lead to misuse, Bloomberg reported Tuesday.
  • In January, the FDA outlined several strategies to formulate new treatments and to make existing opioid analgesics less susceptible to abuse.
  • Orexo is awaiting a July 6 ruling in the US on a medicine that blocks opiate receptors in the nervous system.
  • In June, Nektar Therapeutics announced positive trial results on an experimental drug designed to enter the brain slowly, reducing the euphoria that can lead to addiction.
  • Pharmaceutical companies could introduce chemical combinations that would neutralise the ability to ingest it in non-prescribed manners, or induce an unpleasant sensation which could discourage overuse or alternative administration, according to the news source.
  • "Putting other things in the opiate that make it unattractive and unpleasant to use could create abuse deterrent properties," said Douglas Throckmorton, deputy director for regulatory programs at the FDA.

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