Combining antibiotics changes their effectiveness: Effectiveness of antibiotics altered by combining them with each other, non-antibiotic drugs or even with food additives - (ScienceDaily via NewsPoints Desk)

  • Study findings published in the journal Nature suggest that the effectiveness of antibiotics can be altered by combining them with each other, non-antibiotic drugs or even with food additives, reported ScienceDaily.

  • In the first large-scale screening of its kind, scientists profiled almost 3000 drug combinations on three different disease-causing bacteria.

  • Results showed that while many of the investigated drug combinations lessened the antibiotics' effect, there were over 500 drug combinations which improved antibiotic outcome.

  • A selection of these positive pairings was also tested in multi-drug resistant bacteria, isolated from infected hospital patients, and was found to improve antibiotic effects.

  • Researcher Nassos Typas said "in the future, we could use drug combinations to selectively prevent the harmful effects of antibiotics on healthy bacteria."

  • He noted "this would also decrease antibiotic resistance development, as healthy bacteria would not be put under pressure to evolve antibiotic resistance, which can later be transferred to dangerous bacteria."

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