AstraZeneca to discuss with U.S. FDA changing vaccine trial design - (This is Money via NewsPoints Desk)

  • AstraZeneca will begin discussions this week with the FDA about modifying the design of its experimental COVID-19 vaccine trial to add a likely more effective dosage regime, as reported This is Money.

  • "In terms of how quickly, we will try and do that as quickly as possible," remarked Mene Pangalos, executive vice president of biopharmaceuticals R&D, adding it would be a "matter of weeks."

  • Pangalos said a regimen that includes a half dose being administered followed by a full dose one month later was better tolerated than using two full doses. 

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